ALDP orthologs
Alignment of ALDP proteins in different species
. . . . . .
HUMAN MPVLSRP-RPWRGNTLKRTAVLLALAAYGAHKVYP-----LVRQCLAPARGLQAPAG--E 52
GORILLA MPVLSRP-RPWRGNTLKRTAVLLALAAYGAHKVYP-----LVRQCLAPARGLQAPAG--E 52
CHIMPANZEE MPVLSRP-RPWRGNTLKRTAVLLALAAYGAHKVYP-----LVRQCLAPARGLQAPAG--E 52
MACAQUE MPVLSRP-RPWRGSTLKRTAVLLALAAYGVHKVYP-----LVRQCLAPARGSQAPAR--E 52
COW MTVLSTP-RASRVTTLKRTAVVLALVAYGAHKLYP-----LVRQCLAPARGPQAPAVEGE 54
DOG MPVLSTP-RSSRVTTLKRTALVLALTAYGAHKIYP-----LVRHYLAATRGPQVPAG--E 52
MOUSE MPVLSTP-RPSRVTTLKRTAVVLALTAYGVHKIYP-----LVRQCLTPARGPQVPAG--E 52
RAT MPVLSTPSRPSRVTTLKRTAVVLALTAYGVHKIYP-----LVRQCLTPARGPQVPAG--E 53
KANGAROO_RAT MPVLSTP-RPSRATTLKRTAMVLALTAYGVHKIYP-----LVRQCLALARGPPVPAG--E 52
ZEBRAFISH MSVYSKL-PSQLKKPLVKKAVVLLIALYGVKKLSPYFFGKLKGRTSKQVKGADPLTSNGE 59
*.* * . ..* :.*::* :. **.:*: * * : .:* : *
. . . . .
HUMAN PTQEASG---VAAAKAGMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAALVSRTFLSV 109
GORILLA PTQEASG---VAAAKAGMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAALVSRTFLSV 109
CHIMPANZEE PTQEASG---VAAAKAGMNRVFLQRLLWLLRLLFPRVLCRETGLLALHSAALVSRTFLSV 109
MACAQUE PTQESSG---AAAAKAGMNRVFLQRLMWLLRLLFPRVLCRETGLLALHSAALVSRTFLSV 109
COW PTPDVSGAPVASAGKAGVNQVFLQRLLWLLRLLFPRILCRETGLLALHSAALVSRTFLSV 114
DOG STQEVSG---ATAAKASVNRVFLQRLLGLLRLLFPRTLCRETGLLALHSASLVSRTFLSV 109
MOUSE PTQEASG---ATATKAGMNRVFLQRLLALLRLLFPRVLCRETGLLALHSAALVSRTFLSV 109
RAT STQEASG---ATTAKAGMNRVFLQRLLVLLRLLFPGVLCRETGLLALHSAALVSRTFLSV 110
KANGAROO_RAT PTQEASG---TTAAKTGMNRVFLRRLLVLLRLLFPRILCRESGLLALHSAALVSRTFLSV 109
ZEBRAFISH PLVEAAR---KRKRSPAVNREFFDRLIRLLKILFPRLFCKELGLLGFHSLALISRTFLSI 116
. : : ...:*: *: **: **::*** :*:* ***.:** :*:******:
. . . . . .
HUMAN YVARLDGRLARCIVRKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLALSFRSRLVAH 169
GORILLA YVARLDGRLARCIVRKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLALSFRSRLVAH 169
CHIMPANZEE YVARLDGRLARCIVRKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLALSFRSRLVAH 169
MACAQUE YVARLDGRLARCIVRKDPRAFGWQLLQWLLIALPATFVNSAIRYLEGQLALSFRSRLVAH 169
COW YVARLDGRLARCIVRKDPQAFSWQLVQWLLIALPATFINSAIRYLEGQLALAFRSRLVAH 174
DOG YVARLDGRLARCIVRKDPRAFGWQLLQWLLIALPATFINSAIRYLEGQLALSFRSRLVAH 169
MOUSE YVARLDGRLARCIVRKDPRAFSWQLLQWLLIALPATFINSAIRYLEGQLALSFRSRLVAH 169
RAT YVARLDGRLARCIVRKDPRAFSWQLLQWLLIALPATFINSAIRYLEGQLALSFRSRLVAH 170
KANGAROO_RAT YVARLDGRLARCIVRKDPRAFSWQLLQWLLIALPATFINSAIRYLEGQLALAFRSRLVDH 169
ZEBRAFISH YVANLDGQIVKTIVKKDPRAFVVELTKWLLIAIPATFVNSAIRYLEGQLTLAFRTRLVTH 176
***.***::.: **:***:** :* :*****:****:***********:*:**:*** *
. . . . . .
HUMAN AYRLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTL 229
GORILLA AYRLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTL 229
CHIMPANZEE AYRLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTL 229
MACAQUE AYRLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTL 229
COW AYSLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTTYTL 234
DOG AYSLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTAYTL 229
MOUSE AYGLYFSQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTL 229
RAT AYGLYFSQQTYYRVSNMDGRLRNPDQSLTEDMVAFAASVAHLYSNLTKPLLDVAVTSYTL 230
KANGAROO_RAT AYSLYFTQQTYYRVSNMDGRLRNPDQSLTEDVVAFAASVAHLYSNLTKPLLDVAVTSYTL 229
ZEBRAFISH AYMLYFSDQTYYRVSNMDGRLANPDQSLTEDVVMFAASVAHLYSNLTKPILDVVVTCYTL 236
** ***::************* *********:* ***************:***.** ***
. . . . . .
HUMAN LRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVAN 289
GORILLA LRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVAN 289
CHIMPANZEE LRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVAN 289
MACAQUE LQAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVAN 289
COW VRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVAN 294
DOG LRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVAN 289
MOUSE LRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVAN 289
RAT LRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVAN 290
KANGAROO_RAT VRAARSRGAGTAWPSAIAGLVVFLTANVLRAFSPKFGELVAEEARRKGELRYMHSRVVAN 289
ZEBRAFISH IKTAESKGANTTWPSVIAGIVVALTAKVLRAFSPRFGKLVAEEARRKGDLRYMHSRIIAN 296
:::*.*:**.*:***.***:** ***:*******:**:**********:*******::**
. . . . . .
HUMAN SEEIAFYGGHEVELALLQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAV 349
GORILLA SEEIAFYGGHEVELALLQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAV 349
CHIMPANZEE SEEIAFYGGHEVELALLQRSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAV 349
MACAQUE SEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAV 349
COW SEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAV 354
DOG SEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYIMLEQFLMKYVWSASGLLMVAV 349
MOUSE SEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAV 349
RAT SEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAV 350
KANGAROO_RAT SEEIAFYGGHEVELALLQHSYQDLASQINLILLERLWYVMLEQFLMKYVWSASGLLMVAV 349
ZEBRAFISH SEEIAFYGGHKIEMLQLQRSYNSLSRQINLILFKRLWYVMLEQFLMKYLWSASGLVMVAV 356
**********::*: **:**:.*: ******::****:*********:******:****
. . . . . .
HUMAN PIITATGYSESDAEAVKKAALEKKEEE-LVSERTEAFTIARNLLTAAADAIERIMSSYKE 408
GORILLA PIITATGYSESDAEAVKKAALEKKEEE-LVSERTEAFTIARNLLTAAADAIERIMSSYKE 408
CHIMPANZEE PIITATGYSESDAEAVKKAALEKKEEE-LVSERTEAFTIARNLLTAAADAIERIMSSYKE 408
MACAQUE PIITATGYSETDAEAVKKAALEKKEEE-LVSERTEAFTIARNLLTAAADAIERIMSSYKE 408
COW PIITATGYSESDSETVKKAAQAMKEGE-LVSERTEAFTIARNLLTAAADAIERVMSSYKE 413
DOG PIITATGYSESDSEAVKKAALEMREEE-LVSERTEAFTIARNLLTAAADAIERIMSSYKE 408
MOUSE PIITATGYAESDSEAMKKAALEMKEEE-LVSERTEAFTIARNLLTAAADATERIMSSYKE 408
RAT PIITATGYAESDSEAMKKAALEMKEEE-LVSERTEAFTIARNLLTAAADATERIMSSYKE 409
KANGAROO_RAT PIITATGYSESDSETMKKAAFQKEEEEELVSERTEAFTIARNLLTAAADATERIMSSYKE 409
ZEBRAFISH PIITATGYSKYDSEDVKQAALDMKEED-LVSERTQAFTTARSLLNAAADAVERIMVSYKE 415
********:: *:* :*:** .* : ******:*** **.**.***** **:* ****
. . . . . .
HUMAN VTELAGYTARVHEMFQVFEDVQRCHFKRPR-ELEDAQAGSGTIGRSGVRVEGPLKIRGQV 467
GORILLA VTELAGYTARVHEMFQVFEDVQRCHFKRPR-ELEDAQAGSGTIGRSGVRVEGPLKIRGQV 467
CHIMPANZEE VTELAGYTARVHEMFQVFEDVHRCHFKRPR-ELEDAQAGSGTIGRSGVRVEGPLKIRGQV 467
MACAQUE VTELAGYTARVHEMFQVFEDVQRCHFKRPR-ELEDAQAGSGTIGRSGVRVEGPLKIRGQV 467
COW VTELAGYTARVYEMFQVFEDVQQCRFKRPG-EPEDAHTGSGAIMRSGIRMEGPLQIRGQV 472
DOG VTELAGYTARVHEMFQVFEDVQHCRFKRPG-ELEDTQAGPGAVARSGVHVEGPLQIRGQV 467
MOUSE VTELAGYTARVYEMFQVFEDVKHCRFKRTG-DLEEAQAGPGVMVQSGVHVEGPLKIQGQV 467
RAT VTELAGYTARVYEMFQVFEDVQHCRFKRTG-DLEEAQAGPGSMVHSGVHIEGPLKIQGQV 468
KANGAROO_RAT VTELAGYTARVYEMFQVFEDVQHCRFKRPG-EPEDGHTGSVALVRSGVHIEGPLKIQGQV 468
ZEBRAFISH VTELAGYTARVYEMFEVFEDVRDGVYRRSATEVKPEETGAPQNVTHGMRVEGPLQIRGQV 475
***********:***:*****: ::*. : : .:*. *:::****:*:***
. . . . . .
HUMAN VDVEQGIICENIPIVTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTY 527
GORILLA VDVEQGIICENIPIVTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTY 527
CHIMPANZEE VDVEQGIICENIPIVTPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTY 527
MACAQUE VDVEQGIICENIPIITPSGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTY 527
COW VDVEQGIVCENIPIITPTGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTY 532
DOG VDVEQGIICENIPIITPTGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTY 527
MOUSE VDVEQGIICENIPIITPTGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTY 527
RAT VDVEQGIICENIPIITPTGEVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTY 528
KANGAROO_RAT VDVEQGIICENIPIITPTGDVVVASLNIRVEEGMHLLITGPNGCGKSSLFRILGGLWPTY 528
ZEBRAFISH IDVEQGIKCENLPIITPTGDVVVSSLNMQVDEGMHLLITGPNGCGKSSLFRILSGLWPVY 535
:****** ***:**:**:*:***:***::*:**********************.****.*
. . . . . .
HUMAN GGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHH 587
GORILLA GGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHH 587
CHIMPANZEE GGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMQRKGYSEQDLEAILDVVHLHH 587
MACAQUE GGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVADMRRKGYSEQDLEAILDIVHLHH 587
COW GGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMRRKGYSEEHLEGILDIVHLNH 592
DOG GGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMRRKGYSEQHLEAILDIVHLNH 587
MOUSE SGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSAEDMRRKGCSEQQLEAILGIVHLRH 587
RAT SGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSAEDMRRKGCSEQQLEAILGIVHLRH 588
KANGAROO_RAT GGVLYKPPPQRMFYIPQRPYMSVGSLRDQVIYPDSVEDMRRKGYSEQQLEAILDIVHLHH 588
ZEBRAFISH SGVLYKPSPDHMFYIPQRPYMSVGTLRDQVIYPHSVQEMQEKGITDRQLEEILQTVSLRY 595
.******.*::*************:********.*. :*:.** ::..** ** * *.:
. . . . . .
HUMAN ILQREGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAA 647
GORILLA ILQREGGWEAMCDWKDVLPGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAA 647
CHIMPANZEE ILQREGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAA 647
MACAQUE ILQREGGWEAMCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAA 647
COW ILQREGGWEAVCDWKDVLSGGEKQRVGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAA 652
DOG ILQREGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAA 647
MOUSE ILQREGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAA 647
RAT ILQREGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAA 648
KANGAROO_RAT ILQREGGWEAVCDWKDVLSGGEKQRIGMARMFYHRPKYALLDECTSAVSIDVEGKIFQAA 648
ZEBRAFISH ILEREGGWDAVSDWKDVLSGGEKQRMGMARMFYHKPQYALLDECTSAVSIDVEGKIFEAA 655
**:*****:*:.******.******:********:*:********************:**
. . . . . .
HUMAN KDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIP 707
GORILLA KDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIP 707
CHIMPANZEE KDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIP 707
MACAQUE KDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIP 707
COW KDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIP 712
DOG KDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIP 707
MOUSE KDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIP 707
RAT KDAGISLLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSAARLSLTEEKQRLEQQLAGIP 708
KANGAROO_RAT KDAGIALLSITHRPSLWKYHTHLLQFDGEGGWKFEKLDSATRLSLTEEKQRLEQQLAGIP 708
ZEBRAFISH KDAGISLLSITHRPSLWKYHSHLLQFDGEGGWRFEKLDASTRISLQDEKIRLETQLSGIP 715
*****:**************:***********:*****:::*:** :** *** **:***
. . . .
HUMAN KMQRRLQELCQILGEAVAPAHVPAPSPQGPGGLQGAST 745
GORILLA KMQRRLQELCQILGEAVAPAHVPAPSPQGPGGLQGAST 745
CHIMPANZEE KMQRRLQELCQILGEAVAPAHVPAPSPQGPGGLQGAST 745
MACAQUE KMQRRLQELCQILGEAMAPAQVPAPSSQDPGGLQGAST 745
COW KMQRRLQELCQILG-------------QGPGANQGTAT 737
DOG KMQRRLQELCQILG-------------QGSGVLQGAVP 732
MOUSE KMQGRLQELRQILGEAAAPVQPLVP-----GVPT---- 736
RAT KMQGRLQELRQILGEAAAPVQPLVP-----GIPT---- 737
KANGAROO_RAT KIQGRLQELRQILGEAVAPEKPSAASLPGSGLPT---- 742
ZEBRAFISH KMQQRLTELCRILGEDSSLP------------------ 735
*:* ** ** :***
Last modified | 2017-11-13