The purpose of the adrenoleukodystrophy database is to provide general educational information about ALD. We intend to cover as many aspects of ALD as possible. You should not use our website to diagnose or treat ALD. While we provide information, you should always consult your professional health care provider with any specific disease-related questions or problems you may have.
Contributors are responsible for the reliability of unreviewed data published in this database. While as much effort as possible has been made to ensure that this database is of high quality, the laboratories/investigators that have identified these mutations make no warranty, expressed or implied, as to the accuracy of the information or its suitability for any specific purpose. Users should be very cautious for several reasons:
- A phenotype/genotype correlation in ALD does not exist. It is not possible to predict disease course; not even within individual families.
- The ‘mutation’ may be a technical artefact.
- For many variants of unknown significance (VUS) experimental proof demonstrating that the variant is not pathogenic is lacking.
- Due to the high percentage of unique mutations in ALD, many of the mutations have not been confirmed by independent research groups.
Unpublished mutations may not be used for publication purposes without prior approval from the editor of the database and the laboratories/investigators that have identified these mutations.
Last modified | 2017-11-07